A hat-trick for Ronaldo, one from the penalty spot, one from Benzema and one from Khedira saw Real Madrid cruise past Real Sociedad 5-1, Griezmann replying for the visitors.
Barral and Aduriz were on target for Athletic Bilbao as they beat Levante 2-1, Mikel Rico scoring for the visitors.
Fazio, Vitolo and Bacca found the net for Sevilla as they emerged victorious against Espanyol. Sergio Garcia found the net for Espanyol to make the final score 1-3.